As a hermit, James lived in an open field in the summer and in winter he lived in a cave. On one occasion, he went down to the town of Nisibis to see how the Christian Faith was prospering and to see how Christians live. There, he was elected bishop. He participated in the First Ecumenical Council (Nicaea, 325 A.D.) and protected Orthodoxy against the Arian heresy. It happened once that the infidel Persians with their armies attacked Nisibis. St. James, in a procession with the Cross and banner [Litija] came before the ramparts of the town. Alone he climbed and walked along the rampart not fearing the arrows of the adversary which were aimed at him. Walking along as he did, he prayed to God to preserve the town and the faithful in this manner: "That He [God] would send a plague of flies and mosquitoes on the Persians and by that to cause them to flee from the walls of the town of Nisibis." However, James did not seek the death of his enemies, nor did he seek whatever kind of catastrophe and defeat rather, one small vexation which would cause them to flee from Nisibis. God heard the prayers of His chosen one and sent a plague of flies and mosquitoes upon the Persians, driving them away. Thereby, the town of Nisibis was spared. St. James lived long and honorably. He died peacefully in old age in the year 350 A.D.
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